The aim of our study was to evaluate the frequency of thyroid function abnormalities, antithyroid auto-antibodies and few other well-known autoimmune antibodies [antinuclear antibody (ANA), anti-smooth muscle antibody (SMA), anti-parietal cell antibody (PCA), anti-thyroglobulin antibodies (anti-Tg)] in Iranian patients affected by AA. This evidence concerns the gene TG and Autoimmunity.