SFTPD and infection: The same extent of bronchiole wall thickening was seen in the lungs of both SP-D-/- and SP-D+/+ mice at 24 hrs post infection but there was considerably less cellular infiltration into peribronchial and perivascular areas of SP-D+/+ lungs when compared to SP-D-/- lungs (Fig. 6, arrows 1 for bronchiole wall thickening, arrows 2 for cellular infiltration).