HSPE1 and colorectal carcinoma: 3a), compared to 26 out of 34 Ni of G3 CRC (76%) (fig. 3b). Fig. 2d shows that all Ni of both G1 (fig. 3c) and G3 (fig. 3d) LBC were positive to HSP10. Statistical analyses showed that the difference between the number of HSP60 positive Ni in G1 and G3 LBC was significant (p < 0.01), while statistic difference was not found for HSP10 positivity (p > 0.05). Both HSP60 and HSP10 positivity was often co-localised within vascular (fig. 3e) and nervous (fig. 3f) structures invaded by neoplastic tissue in both Ti and Ni.