2a), while a similar number of HSP10 positive elements were present in both groups (mean: respectively 74% and 75%) (fig. 2b). Normal epithelium above the infiltrating neoplasms resulted commonly negative or with few scattered positive elements (fig. 1b), similarly to what observed in the biopsies of normal colonic mucosae (data not shown). This evidence concerns the gene HSPE1 and neoplasm.