When levels were compared between node positive and node negative tumours, no significant difference was seen with either enzyme (5189 ± 2244 vs 13222 ± 10821 p = 0.48, and 33.2 ± 10 vs 18.5 ± 6.3, p = 0.21, for TBXA2R and TBXAS1, respectively). Here, TBXAS1 is linked to neoplasm.