Data suggesting that methylation of gene promoters in patients with cervical cancer is a common phenomenon were reported by another group that analyzed DAPK, p16, and MGMT genes; these authors also found a strong correspondence between methylation in serum and in primary tumors with methylation frequencies in serum of 40, 10, and 7.5% of these genes, respectively [236]. The gene discussed is CDKN2A; the disease is cervical cancer.