In our study of 54 GBM patients, 43% (n = 23) failed to express the EGFR, 57% (n = 31) were positive for the pan-EGFR stain and of those that expressed EGFR, 31% (n = 17) also expressed the EGFRvIII variant while 26% (n = 14) failed to express EGFRvIII. This evidence concerns the gene EGFR and glioblastoma.