Interestingly, results showed that the IN mutant D64E virus infection induced the highest level of β-Gal positive cells, whereas infection with viruses containing IN mutants KK215,9AA, KK240,4AE or RK263,4AA yielded much lower levels of β-Gal positive cells, which only reached approximately 11%, 5% or 26% of the level of D64E virus infection (Fig. 3B). This evidence concerns the gene CD44 and infection.