It seems to be unlikely since 1) the effect of this mutant on nuclear import was not as dramatic as KK215,9AA mutant (as shown in Fig. 5); 2) Wiskerchen et al have reported that infection of MAGI cells with two other IN mutants K236A/K240A and K244A/E246A mutants, that are located in the same region as our KK240,4AE mutant, resulted in 0 and 4 β-Gal positive cells, while infection of class I IN mutants produced 700 to 1400 β-Gal positive cells [15]. This evidence concerns the gene CD44 and infection.