A 4 h chromium release assay was performed on each of the three RCC lines and in each case, we observed significantly enhanced killing of the renal cell lines by 5T4.CD3ζ-transduced lymphocytes when compared to either the MFE.CD3ζ transduced or the mock-transduced lymphocytes (Figure 3). This evidence concerns the gene CD247 and renal cell carcinoma.