VEGFA and colorectal cancer: In colorectal cancer, it was found that expression of VEGF isoform with molecular weight 23 kDa was significantly correlated with a smaller tumour size (maximum diameter < 5 cm, p < 0.05), whereas the 26 kDa VEGF isoform was significantly correlated with advanced clinical stage and metastasis of the tumour (p < 0.01).