Although expression of VEGF121 mRNA has been previously reported to be correlated with lymph node metastasis [10] of primary lung cancer and the invasiveness of bladder cancer [24], in our study we found that level of the 18 kDa VEGF protein, which believed to be VEGF121 [16], was equally expressed in both normal and tumour tissues of colorectal, and predominately expressed in normal tissues of the lung. The gene discussed is VEGFA; the disease is lung carcinoma.