The type III epidermal growth factor mutation variously named, EGFRvIII, ΔEGFR, de2-7EGFR and mEGFR is the most common mutation in the EGFR gene and is frequently found in tumours of the breast, ovary, prostate, lung and in particular those of the brain (Garcia et al, 1993; Moscatello et al, 1995; Olapade-Olaopa et al, 2000; Pedersen et al, 2001; Ge et al, 2002). This evidence concerns the gene EGFR and neoplasm.