VEGFD and neoplasm: Whether the expression of VEGF-C and VEGF-D also plays a role in lymphangiogenesis and the formation of lymph node metastases in human tumours, as described for immunodeficient mice (Karpanen et al, 2001; Mandriota et al, 2001; Skobe et al, 2001; Stacker et al, 2001), is still unknown.