Microalbuminuria correlates with cardiovascular autonomic dysfunction and insulin resistance in type 2 diabetic patients.29 In hypertensive subjects, the inflamatory injury in the kidney structures consequent to that of myocardial infarction causes a greater albumin leak.30 However, precise underlying pathophysiologic mechanisms of the association between proteinuria and unfavorable cardiovascular outcome among persons with no history of diabetes mellitus, hypertension, acute myocardial infarction, or stroke have not been totally given. This evidence concerns the gene ALB and stroke disorder.