Genes that were significantly up-regulated in both microarray and real-time PCR in the two IBD subtypes (compared to normal controls), include cadherin-11 (CDH11), decay accelerating factor for complement (DAF), immunoglobulin heavy constant gamma 1 (IGHG1), mucin 1 (MUC1), phospholipase A2, group IIA (PLA2G2A), and tissue inhibitor of metalloproteinase 1 (TIMP1). This evidence concerns the gene IGHG1 and inflammatory bowel disease.