Of 43 MSI-H cancers, 14 failed to express the MLH1, seven failed to express MSH2, while 22 expressed MLH1 and MSH2. Of 32 MSI-L/MSS cancers, 28 expressed MLH1 and MSH2, three failed to express MLH1 and one failed to express MSH2. Five MSI-H cancers failed to express the MSH6, of which one failed to express MLH1, three failed to express MSH2 and only one cancer failed to express MSH6 alone (Table 3). Here, MSH6 is linked to cancer.