UBE2C and carcinoma: While a weak staining is detectable in follicular adenomas (Figure 2C), higher levels of UbcH10 were recorded in papillary (median value 2.2% of positive cells; range 0.9–4.1%), follicular (median value 2.8% of positive cells; range 1–6.1%) and poorly differentiated (median value 10.4% of positive cells; range 8–14.9%) carcinomas, signal being always easily detectable in the nuclei of scattered neoplastic cells (Figure 2D, E and F).