IFNA1 and familial pancreatic carcinoma: We previously reported that an intratumoral injection of an adenoviral vector expressing the human IFN-α gene, AxCA-IFN (2.5 × 108 PFU), effectively suppressed the growth of nude mouse subcutaneous tumours of the AsPC-1 human pancreatic cancer cells (Hatanaka et al, 2004).