IL1B and parasitic infectious disease: Gyan et al. [6] reported that, in Ghanaian Children, levels of parasitemia were significantly higher in uncomplicated malaria patients possessing the IL1B 3953T allele (i.e., 3953T/T and 3953C/T genotypes) than those possessing only 3953C (i.e., 3953C/C genotype), although this polymorphism and the IL1RA variable number of tandem repeat (VNTR) polymorphism were not associated with cerebral malaria.