The mean LDL level in women with T2DM and PCO was significantly higher than in controls with PCO (127 vs. 97 mg/dl; P < 0.03); other parameters including diastolic blood pressure, BMI, waist hip ratio, cholesterol, triglycerides, HDL, VLDL, LH, testosterone and androstenedione and ovarian volume were comparable between women with PCO and with or without T2DM. Here, PLOD1 is linked to type 2 diabetes mellitus.