The determined classifiers could be subdivided into three categories: those genes/probe sets capable to distinguish between (a) normal breast and breast cancer tissues (2 genes, FHL1 and CLDN5), (b) pCR or cCR from unfavorable outcomes (PR or NC) (31 probe sets or "favorable response signature"), and (c) NC and PR (26 probe sets or "poor response signature"). Here, FHL1 is linked to breast carcinoma.