The risk of breast cancer in women who inherit a germline mutation in the BRCA1 gene can be as high as 20% by the age of 40 and 50% by the age of 50 [1] and as high as 13% by the age of 40 and 60% by the age of 50 in BRCA2 mutation carriers [2]. Here, BRCA1 is linked to breast carcinoma.