SETD2 and neoplasm: Low levels of nuclear staining (HIF-1α ≥ 1% and < 5%) were found in 11,6 % (9/85) of the tumour specimen with detectable HIF-1α-expression, high levels of HIF 1-α expression (≥ 5%) were found in 52,9% (45/85) of the positive tumour specimens and very high levels (≥10%) were found in 35,9% (30/85) of the cases.