A related body of research suggests that chronic exposure to social stressors associated with socioeconomic deprivation may result in repeated activation—and ultimately harmful dysregulation—of physiological systems that respond to stress, thereby increasing risk of elevated blood pressure, insulin resistance, and visceral fat deposition and thus risk of cardiovascular disease, obesity, and diabetes [37–39]. The gene discussed is INS; the disease is obesity due to melanocortin 4 receptor deficiency.