On Kaplan-Meier analysis (figure 2), patients with p53(-) tumours demonstrated a significantly longer mean disease specific survival (DSS) of 76 (95% CI 69–83) months, as compared with a mean DSS of 64 (95% CI 57–71) months in patients with p53(+) tumours (p = 0.0240). The gene discussed is TP53; the disease is neoplasm.