Additional strong correlations were noted between the p53(-) / Bcl-2(+) phenotype and DSS on univariate analysis (p = 0.004), and on Kaplan-Meier analysis, with a mean DSS of 84 (95%CI 75–92) months in patients with p53(-) / Bcl-2(+) tumours compared with a mean survival of 65 (95% CI 59–71) months in the remaining patients (figure 4) (p = 0.0032). The gene discussed is TP53; the disease is neoplasm.