However, even if GSTP1 (Townsend and Tew, 2003) and MRP1 (Kruh and Belinsky, 2003) have been implicated, sometimes in a coordinated fashion (Harbottle et al, 2001), in the development of resistance toward chemotherapy agents, only a few studies have investigated their role in the drug resistance of MM and the results remained contradictory (Wang et al, 1989; Schadendorf et al, 1995a; Serrone and Hersey, 1999; Ichihashi and Kitajima, 2001). The gene discussed is GSTP1; the disease is Miyoshi myopathy.