BRCA1 and cancer: In contrast to BRCA1 tumours, the BRCA2 tumours diagnosed in patients 50 years or older were more often ER- (52.6% vs 25.6%, P = 0.02) and PR- (80.0% vs 54.4%, P = 0.036) than non-BRCA1/2 cancers among the same age group.