CD8A and cervical squamous intraepithelial neoplasia: In a CD8 response, the highest frequency of spots (1538 spots per 1 × 106 CD8+ T cells) was obtained from a patient with no CIN (patient 27), again in response to an E6 peptide (KLPQLCTELQTTIHDIILECVYCKQQLLRREV; aa 18–49).