In addition, EWS gene fusions with various partners are described in clear cell sarcoma, desmoplastic small round cell tumours, chondrosarcoma, and myxoid liposarcoma, suggesting that EWS fusion proteins are functional for various cell types of mesenchymal origin and that restrictions in humans are dictated largely by the cells in which the chromosomal translocations occur. This evidence concerns the gene EWSR1 and desmoplastic small round cell tumor.