TF and cancer: The most frequent reports on coagulant proteins and cancer interactions include factor III (tissue factor; TF) [11], TF-factor VIIa [12,13], factor Xa [14], factor IIa (thrombin)-factorII receptors (also called proease-activated receptors (PARs) [15], and factor XIIIa-factor Ia (fibrin) (Table 1) [16].