Others studies have shown that phosphorylation of the Src nonreceptor tyrosine kinase is associated with inherent or acquired gemcitabine resistance in pancreatic cancer cells (Duxbury et al, 2004); however, we detected no differences in phosphorylated Src between NRP-1-transfected and mock-transfected FG cells (data not shown). This evidence concerns the gene NRP1 and familial pancreatic carcinoma.