VEGFA and neoplasm: In particular, VEGF (VEGF-A, vascular permeability factor) overexpression has been associated with tumour progression and poor prognosis in a number of tumour systems (Dvorak et al, 1995; Takahashi et al, 1995; Fujimoto et al, 1998; Berns et al, 2003; Gorski et al, 2003).