Analysis of peripheral blood MPs from patients with SLE has found that IFN-inducible genes are upregulated in almost all patients with SLE [2,3,67] and the genes upregulated in SLE patients were similar to those upregulated in peripheral blood MPs stimulated in vitro with IFN-α [1-3,67]. The gene discussed is IFNA1; the disease is systemic lupus erythematosus.