Lynch et al also sequenced the entire coding region of the EGFR gene in tumours from 25 patients with NSCLC not treated with gefitinib, including 15 patients with bronchioloalveolar carcinoma, and found these mutations in two patients, both of whom had bronchioloalveolar carcinoma. This evidence concerns the gene EGFR and bronchioloalveolar carcinoma.