BRAF and melanoma: Comparing mutations of B-raf exon 15 in cutaneous/subcutaneous metastases with those in primary melanomas [6] by Fisher's exact test, no statistically significant differences in the proportion of mutations in general (p = 0.85; odds ratio = 0.92, 95% confidence interval 0.39–2.13), T1796A (p = 0.56; odds ratio = 0.77, 95% confidence interval 0.33–1.81), V599 (p = 0.56; odds ratio = 0.77, 95% confidence interval 0.33–1.81), V599E (p = 0.40; odds ratio = 0.68, 95% confidence interval 0.26–1.72) and V599K (p = 0.77; odds ratio = 1.22, 95% confidence interval 0.30–4.94) could be observed.