Among CFS subjects, the 10 who reported being ill for ≤ 5 years had lower levels of autoantibodies to MAP2 (median value of 18, range 12 – 20) compared to the 12 CFS subjects who have been ill for >5 years (median value of 8, range 6 to 10) (p = 0.025). This evidence concerns the gene MAP2 and myalgic encephalomeyelitis/chronic fatigue syndrome.