CCL2 and neoplasm: In particular, chemokine (C-C motif) ligand 2 (CCL2, previously known as monocyte chemotactic protein-1, MCP-1), which is a potent chemoattractant for macrophages (Sica et al, 1990), and also T cells (Taub et al, 1995), has been found to be expressed in ovarian tumours (Negus et al, 1995; Burke et al, 1996) and appears to be an important determinant of the leukocyte infiltrate into tumours (Zacchariae et al, 1990; Rollins, 1991; Bottazzi et al, 1992; Negus et al, 1997; Zhang et al, 1997).