OSM and chondrosarcoma: Using the SW1353 chondrosarcoma cell line as a model in which to look at the regulation of metalloproteinase and TIMP gene expression, we profiled the expression of all MMPs, ADAMTSs, and TIMPs in cells stimulated with IL-1α and OSM in the absence or presence of HDAC inhibitors at the doses used for the cartilage explant experiments above.