At pre PI-ART, the mean age of the 72 patients was 41 (SD 9, range 23 – 65) years, 59 were of Swedish origin, 61 had prior antiretroviral treatment with only nucleoside analogue reverse transcriptase inhibitors, 32 had a CD4 count of <200 × 106 cells l-1 and 28 had an AIDS diagnosis. The gene discussed is CD4; the disease is AIDS.