In this study we directly compared levels of IL-1α-induced gene expression by analysing the levels of 11β-hydroxysteroid dehydrogenase (11βHSD) types 1 (11βHSD-1) and 2 (11βHSD-2), cyclooxygenase-2 (COX-2), IL-1 receptor (IL-1R) and glucocorticoid receptor α (GRα) mRNA between normal HOSE cells and cell lines derived from poorly differentiated (SKOV-3, BG-1, PEO-4) and well-differentiated (PEO-14) ovarian adenocarcinoma. The gene discussed is IL1R1; the disease is ovarian adenocarcinoma.