EZH2 and cancer: Recent studies have shown that EZH2 is highly expressed in several advanced cancers (Raaphorst et al, 2000; van Kemenade et al, 2001; Visser et al, 2001; Sellers and Loda, 2002; Varambally et al, 2002; Kleer et al, 2003; Rhodes et al, 2003; Raaphorst et al, 2003; Dukers et al, 2004; Foster et al, 2004).