Tumour relapse was documented in 136 of 285 patients (47.7%) in the therapy arms containing LEV (treatment arms 2 and 4), in 113 of 287 patients (39.4%) in the therapy arms not containing LEV (arms 1 and 3), in 134 of 287 patients (46.7%) treated with IFN (arms 3 and 4) and in 125 of 285 patients (43.8%) not treated with IFN (arms 1 and 2). This evidence concerns the gene IFNA1 and neoplasm.