TGFA and head and neck squamous cell carcinoma: The EGF receptor as well as its principal ligand TGF-α are expressed in approximately 80% of HNSCC (Grandis et al, 1996; Grandis et al, 1998) and play an important role in the biology of this disease (Barrandon and Green 1987; Grandis et al, 1998; O-charoenrat et al, 2000; Veikkola et al, 2000; Ang et al, 2002).