Among FGFs, basic FGF (bFGF) which binds to specific RTKs, FGFRs (Mohammadi et al, 1997), is the most active growth factor for endothelium and several studies have demonstrated its expression in breast cancer (Luqmani et al, 1992; Colomer et al, 1997; Smith et al, 1999). The gene discussed is FGF2; the disease is breast cancer.