F2 and Varicose veins: We got the following ranking of the predictive power to explain the occurrence of new VTE cases during a theoretical 10-year period (defined by our model) in declining order: Medical history of VTE, family history of VTE (1st degree relatives), age at baseline 1993, body mass index (BMI), factor V Leiden (FVL) or prothrombin mutation (PTM), family history of varicose veins, protein C, AT level, hormone ever use, MTHFR carrier status, and OC ever use.