Interestingly, importance of this molecule was shown in a model of colorectal carcinoma where transfection with CEACAM6 inhibited anoikis (10), high CEACAM6 predicted high risk patients with resectable colorectal cancer (9) and CEACAM6 gene silencing decreased resistance to anoikis in vitro leading to inhibition of metastatic ability in mouse model (11). The gene discussed is CEACAM6; the disease is colorectal carcinoma.