Nevertheless, all agree that the characteristics of the metabolic syndrome include atherogenic dyslipidemia, a prothrombotic state, insulin resistance, hypertension, abdominal obesity, as well as elevated microalbuminuria, increased fibrinogen, decreased plasminogen activator, elevated plasminogen activator inhibitor-1, increased blood viscosity, and increased uric acid [1]. The gene discussed is SERPINE1; the disease is metabolic syndrome.