Figure 3A shows fluid phase endocytosis by DC of albumin labelled with BODIPY, a fluorescent dye which is quenched extracellularly and hence specifically demonstrates cell uptake. Fluorescence levels were slightly reduced (though still high) on irradiation of IDC, while 30 Gy did not affect uptake by MDC. When phagocytic capacity by irradiated DC was assessed using uptake of fluorescently labelled human SW480 tumour cells, there was again reduced (though still significant) uptake on irradiation by IDC, and no change for MDC (Figure 3B). This evidence concerns the gene ALB and neoplasm.