Though we have reported on use of calcium channel blockers and ACE inhibitors in relation to cancer in general in North Jutland County, Denmark, we did not look in any detail at RCC risk in relation to the wide variety of specific AHTs (Olsen et al, 1997; Sorensen et al, 2000; Friis et al, 2001); these earlier studies had relatively short follow-up periods, ending in 1993, 1995 and 1996, respectively. Here, ACE is linked to renal cell adenocarcinoma.