RXRA and Huntington disease: In view that HD improved the binding of hTRβ1-hRXRα to DR-4 response element, and that previous studies showed that uremic solutions inhibited hVDR-RXRα binding to DR-3-response element (VDRE) [26,27,29] we decided to determine whether uremic plasma collected before and after hemodialysis has the same effect on hVDR-RXRα binding to DR-3.