CCND1 and gastric adenocarcinoma: For example, unlike AGS-B cells (Song et al, 2003b), in AGS-E cells, a related human gastric adenocarcinoma cell line overexpressing the gastrin receptor, G-17 induction of cyclin D1 transcription was mediated through both β-catenin and CREB pathways (Pradeep et al, 2004).