GAST and colorectal carcinoma: A prospective study by Thorburn et al (1998) suggested that hypergastrinemia is associated with an increased risk for colorectal cancer (CRC), and numerous studies have demonstrated that gastrin stimulates the growth of malignant colorectal adenocarcinomas (Wang et al, 1996; Malecka-Panas et al, 1997; Baldwin & Shulkes, 1998; Nakata et al, 1998; Koh et al, 1999; Stepan et al, 1999; Smith & Watson, 2000).