GAK and invasive carcinoma: On the other hand, the average expression levels of 12 (Eph, gp130, GST-II, Rho 8, MUC-2, Ras-GAP, p120, MDR1, αN-catenin, Egr-2, PMS1, and GAK) of the 32 genes were significantly lower in the early invasive carcinoma group than in the adenoma group (Table 3).