Mean contents of PDGF, bFGF and VEGF were higher in tumours from control animals (PDGF=1,195±261, bFGF=893±4, and VEGF=154±7 pg mg−1 of tissue) than in tumours of animals treated with L40 (PDGF=609±84, P=0.05; bFGF=857±12, P=0.035; and VEGF=131±4 pg mg−1, P=0.011) and those treated with L80 (PDGF=451±45, P=0.018; bFGF=827±14, P=0.001; and VEGF=105±19 pg mg−1, P=0.013). The gene discussed is FGF2; the disease is neoplasm.